Nicotine may also increase production of the enzyme that breaks down collagen, accelerating the formation of wrinkles. When collagen breakdowns coupled with repetitive lip pursing and the squinting associated with shielding the eyes from smoke, fine lines and wrinkles become even more apparent.
Smokers lose vitamin C, vitamin B12, B5 and B6. Many people do not realize that vitamin C destroys B vitamins and will take the two vitamins together. Those two vitamins must be taken at least an hour apart. Tests have shown that smokers lose about 25mg of Vitamin C per cigarette.
Smokers in their 40s often have skin as wrinkled as non-smokers in their 60s, and smokers are twice as likely to develop skin cancer.